ABSTRACT
Objective:To assess the clinical efficacy of low-level laser therapy(LLLT)for the treatment of burning mouth syndrome(BMS)in elderly patients.Methods:As a randomized controlled study, 60 elderly BMS patients treated in the department of stomatology of Beijing Hospital from September 2018 to August 2021 were randomly divided into a laser group and a control group, including 7 man and 53 women, with an average age of(68.27±6.38)years.Patients in the laser group were treated with LLLT, and patients in the control group were treated with non-energy red light and oryzanol.The visual analogue scale and self-rating anxiety and depression scale were used to evaluate the two groups of patients.Results:After LLLT, the effectiveness rate of the laser group was 86.67%(26/30)on the 28th and 90th day, which was significantly higher than 63.33%(19/30)of the control group( χ2=4.356, P=0.037). When data for pre-treatment, the 28th day after treatment and the 90th day after treatment for the laser group were compared, results showed that after LLLT, pain symptoms of BMS patients were relieved and it lasted for some time, and anxiety and depression also improved, but there were episodes of relapse as time went on.Visual analogue scale and self-rating anxiety scores and depression scale scores of BMS patients for pre-treatment, the 28th and 90th days after treatment in the two groups were compared.Only self-rating anxiety scale scores of the laser group was lower than those of the control group on the 28th day, with statistical significance( t=2.622, P=0.011), indicating that LLLT could alleviate anxiety for BMS patients in the short term, but had no significant effect on patient depression.However, in the long term, LLLT had no significant effect on relieving anxiety and depression. Conclusions:LLLT has a certain effect on improving pain symptoms and anxiety in elderly BMS patients.
ABSTRACT
A patient with intractable glossalgia was successfully treated with a combination of three Kampo medicines : orengedokuto, bukuryoin, and kososan extracts. Then, 3 more patients with glossalgia were administered similar treatment based on the experience of the first case. The clinical features of these four patients and the efficacy of the combination Kampo treatment are reported herein. <br>A 61-year-old man with a 3-year history of glossalgia had been treated with psychopharmaceuticals for 4 months at another hospital, without any relief from symptoms. Upon referral to this Kampo clinic, the patient was treated with goreisan extract, daisaikoto extract, or other Kampo medicines, but these medicines were not effective. The prescription was then changed to a combination of orengedokuto, nichinto, and kososan extracts, which ameliorated the glossalgia symptoms almost by half. Furthermore, the glossalgia improved completely after the nichinto extract in the Kampo combination was replaced with bukuryoin extract. <br>After successful treatment of the first patient, three other patients were treated with the same Kampo combination. Two patients showed improvement within 2 weeks, but the combination treatment was ineffective in the other patient, whose symptoms finally improved with a zinc supplementation from Polaprezinc. The clinical features of the patients with good outcome were generally characterized by a combination of symptoms such as glossalgia, tendency toward depression, and digestive symptoms. <br>The combination treatment was prescribed as a substitute for seinetsugeutsuto decoction, and it was effective in three of the four patients with glossalgia. These results indicate that the combination treatment could be a candidate medicine to treat glossalgia.
ABSTRACT
Abstract The aim of this study was to assess the effectiveness of low intensity laser therapy in patients with Burning Mouth Syndrome (BMS). Thirty BMS subjects were randomized into two groups - Laser (LG) and Placebo (CG). Seven patients dropped out, leaving 13 patients in LG and 10 patients in CG. Each patient received 4 irradiations (laser or placebo) twice a week, for two consecutive weeks (blinded to the type of irradiation received). Infrared laser (AsGaAI) irradiations were applied to the affected mucosa in scanning mode, wavelength of 790 nm, output power of 20 mW and fluence of 6 J/cm2. A visual analogue scale (VAS) was used to assess the therapeutic effect before and after each irradiation, and at all the control time periods: 7, 14, 30, 60 and 90 days after the last irradiation. One researcher delivered irradiation and another recorded the results. Both researchers were blinded, the first to the results, and the second to the type of radiation applied. The results were categorized according to the percentage of symptom level variation, and showed a statistically better response in LG in only two categories of the control checkpoints (p=0.02; Fisher's Exact Test). According to the protocol used in this study, low intensity laser therapy is as beneficial to patients with BMS as placebo treatment, indicating a great emotional component of involvement in BMS symptomatology. Nevertheless, there were positive results in some statistical analyses, thus encouraging further research in BMS laser therapy with other irradiation parameters.
Subject(s)
Humans , Male , Female , Adult , Aged , Aged, 80 and over , Burning Mouth Syndrome/radiotherapy , Low-Level Light Therapy/methods , Radiation Dosage , Time Factors , Placebo Effect , Treatment Outcome , Lasers, Semiconductor/therapeutic use , Visual Analog Scale , Middle AgedABSTRACT
Objetivo: Avaliar os níveis de ansiedade e depressão, e medir a velocidade do fluxo salivar estimulado em indivíduos portadores da Síndrome da Ardência Bucal (SAB). Método: Um total de 60 indivíduos fez parte deste trabalho, dos quais 30 eram portadores da Síndrome da Ardência Bucal (grupo-caso) e 30 eram indivíduos saudáveis (grupo-controle). Os indivíduos foram submetidos a um exame físico e à coleta de saliva total estimulada para análise da velocidade do fluxo salivar, além de responderem ao questionário Hospital Anxiety and Depression Scale (HADS). Resultado: No grupo-caso, 93% eram mulheres com média de idade de 61,3 anos. A língua mostrou-se a região bucal mais acometida pela sensação de queimação. Nos indivíduos com a Síndrome da Ardência Bucal, 86% dos pacientes sofriam de ansiedade e 73% de depressão; enquanto no grupo-controle, 46,7% dos indivíduos apresentaram algum nível de ansiedade e 23,3%, de depressão. Os testes do Qui-Quadrado e exato de Fischer revelaram haver diferença significativa entre os grupos em função dos níveis de ansiedade e depressão (p = 0,01). A sialometria revelou que as médias da velocidade do fluxo salivar total estimulada para os grupos-caso e controle foram de 1,02 e 1,06 mL/min, respectivamente (p> 0,05). Conclusão: A presença de alterações psicológicas ? tais como a ansiedade e a depressão ? pode representar um fator desencadeante da Síndrome da Ardência Bucal; porém, a velocidade do fluxo salivar não parece estar relacionada com essa síndrome.
Aim: To evaluate anxiety and depression levels and measure stimulated whole saliva flow rate in individuals with burning mouth syndrome. Method: The population analyzed consisted in 30 individuals with the syndrome (case group) and 30 healthy subjects (control group). Both groups were assessed by physical examination, stimulated flow rate analysis and answered the questionnaire HADS. Result: In the case group, 93% were women with a mean age of 61.3 years. Oral burning sensation was more frequent at the tongue. In those patients with burning mouth syndrome, 86% had suffered from anxiety and 73% depression; while in the control group: 46.7% of subjects had some level of anxiety and 23.3% depression. There were statistical differences between groups according to the anxiety and depression levels by Qui-square and Fischer tests (p = 0.01). Sialometry showed rates to the stimulated whole saliva flow rate case and control groups of 1.02 and 1.06 mL/min, respectively (p > 0.05). Conclusion: Psychological disorders such as anxiety and depression may represent a predisposing factor of the BMS, though the decreased saliva flow rate is not a constant condition in this syndrome.